I saw Diresta use spray adhesive to keep his parts down. I tried it and it worked well, but left gunk on the part. I was using a downcut bit, which might help. Maybe a different spray adhesive would have left less gunk.
It can always be used you just have to get creative. If you were doing a large 3D piece do it all but don’t go all they way through by moving the piece up a few mm, then use the 2D cut with tabs to cut it out.