All (or Any) -
Would a spindle like this: 2200KW spindle (amazon link) be a good fit for the MPCNC?
The spindle alone is 12lbs. plus the coolant… The DeWalt 661 is only 4.6lbs.
My guess is a qualified ”probably not", but you might be able to shorten your Z axis, beef up the power of your stepper(s), and maybe get it to work.