Today, I started a print in some HB green PLA and I knew I would run out before I finished it, but I don’t have any more HB PLA. So I let it print, and when it ran out, I paused and stuffed in some other PLA I had (It’s purple “3D Solutech” PLA). I didn’t change a single setting. I didn’t change the temperature, I didn’t change any flow rates, nothing.
I just want to point out that even though there are tough prints that need precise calibration of filament temperature and extrusion and stuff, there is a pretty big allowable margin of error. It’s easy to get caught up in caliper land and forget that.